Small Intestinal Bacterial Overgrowth (SIBO) 2 Hour – Breath #2306

Description

The SIBO (Small Intestinal Bacterial Overgrowth) Test by Genova Diagnostics is a non-invasive breath test used to detect abnormal bacterial growth in the small intestine.

After ingestion of a lactulose solution, breath samples are collected over time to measure hydrogen (H₂) and methane (CH₄) gases produced by bacterial fermentation.

👉 As shown in the report, gas levels are tracked across multiple time points and interpreted based on rise patterns

This allows identification of early fermentation in the small intestine, a hallmark of SIBO.

🔬 What This Test Measures

1. Hydrogen Gas (H₂)

• Produced by bacterial fermentation

👉 Rise ≥ 20 ppm within 90 minutes suggests SIBO

2. Methane Gas (CH₄)

• Produced by methanogenic organisms

👉 ≥ 10 ppm at any point indicates methane overgrowth

3. Gas Patterns Over Time

• Early rise → small intestine overgrowth
• Late rise → normal colonic fermentation

🔬 2 Hour vs 3 Hour Test

2-Hour Test

• Standard clinical test
• Focus on early detection

3-Hour Test

• Extended analysis
• Useful for slow transit or constipation

👉 Provides broader fermentation mapping

🧠 Clinical Insights

• Diagnoses SIBO
• Differentiates hydrogen vs methane dominance
• Identifies fermentation-related digestive issues
• Supports IBS evaluation

Methane-dominant overgrowth has been associated with constipation and slower gut motility

👤 Who Should Consider This Test

• Bloating after meals
• IBS symptoms
• Chronic gas
• Constipation or diarrhea
• Food intolerance

⚠️ Limitations

• ❌ Does not identify specific bacteria
• ❌ No microbiome composition
• ❌ No immune response measurement

👉 This test detects functional bacterial overgrowth only

🔷 Functional vs Immune Testing (Important Section)

👉 Use Genova to answer:
“Do I currently have SIBO?”

👉 Use Cyrex to answer:
“Has SIBO triggered immune damage?”