Estrogen Metabolism Assessment #4213

Description

The Estrogen Metabolism Assessment is a targeted urine test that evaluates how estrogen is metabolized into different pathways, providing insight into hormonal balance and metabolic patterns.

Using high-precision LC-MS/MS technology, the test measures specific estrogen metabolites and their ratios, helping clinicians understand how estrogen is being processed rather than simply measuring total hormone levels.

What This Test Measures

Estrogen Metabolites

• 2-Hydroxyestrone + 2-Hydroxyestradiol [2-OH (E1 + E2)]
• 16α-Hydroxyestrone (16α-OH E1)

Key Ratio

• 2-OH / 16α-OH ratio

Supporting Marker

• Creatinine (for urine normalization)

👉 Results are normalized to creatinine for accurate interpretation of urinary hormone metabolites

Clinical Insights

• Evaluates how estrogen is metabolized into different pathways
• Identifies relative balance between 2-hydroxy and 16α-hydroxy pathways
• Provides insight into estrogen metabolic patterns rather than total hormone levels
• Helps guide clinical interpretation of estrogen-related symptoms

Who Should Consider This Test

• Suspected estrogen imbalance
• Hormone-related symptoms (e.g., PMS, irregular cycles)
• Monitoring estrogen metabolism patterns
• Hormonal health assessment in both men and women

Sample Collection

• Urine sample

Why Choose This Test?

Standard Hormone Testing

• Measures estrogen levels only

Estrogen Metabolism Assessment

• Evaluates how estrogen is processed into different metabolites

👉 Provides a more functional view of estrogen metabolism using specific metabolite ratios