Cyrex Array 20 — Blood-Brain Barrier Permeability Screen

Description

Cyrex Array 20 — Blood-Brain Barrier Permeability Screen™

A compromised blood-brain barrier (BBB) allows toxins, pathogens, and immune complexes into the brain — driving neuroinflammation, cognitive decline, and mood disorders. Cyrex Array 20 measures immune reactivity to six key BBB proteins, quantifying the degree of barrier breakdown.

Antigens Tested (IgG + IgA):

• Claudin 5 + Occludin — tight junction proteins maintaining barrier integrity
• S100B — astrocyte damage/activation marker (elevated when BBB is breached)
• Glial Fibrillary Acidic Protein (GFAP) — astrocyte structural protein, neural injury marker
• Myelin Basic Protein (MBP) — myelin sheath integrity
• Alpha + Beta Tubulin — neuronal cytoskeletal damage

Clinical Applications:

• Brain fog, cognitive decline, memory loss
• Mood disorders, anxiety, depression with neurological involvement
• Post-concussive syndrome or traumatic brain injury
• Multiple sclerosis and neuroinflammatory conditions
• Mould illness, heavy metal toxicity with CNS symptoms

Sample Type:

Blood serum — single blood draw.

Ref: HSE1375