Organic Acids Profile (OAp) — Urine (DSL)

Description

Organic Acids Profile (OAp) — Urine

The Organic Acids Profile (OAp) measures a targeted set of urinary organic acid metabolites using mass spectrometry, providing insight into mitochondrial energy production, B vitamin sufficiency, fatty acid oxidation, detoxification pathways, and gut microbial by-products. It is a core functional medicine test for evaluating root causes of fatigue, brain fog, and metabolic dysfunction.

Metabolite Categories Measured:

• Krebs Cycle / Energy Metabolism: Citrate, Isocitrate, Succinate, Fumarate, Malate, Alpha-ketoglutarate — identifies mitochondrial bottlenecks
• B Vitamin Functional Markers: Methylmalonate (B12 deficiency), Xanthurenate (B6 deficiency), Formiminoglutamate (folate), FIGlu
• Fatty Acid Oxidation: Suberate, Adipate, Ethylmalonate — impaired fat burning marker
• Amino Acid / Detox Markers: Pyroglutamate (glutathione), Orotate (urea cycle), Glucarate (Phase II detox)
• Gut Microbial Markers: Indican (bacterial putrefaction), DHPPA (Clostridia), Benzoate, Hippurate, Tricarballylate
• Neurotransmitter Metabolites: Homovanillate (dopamine), Vanilmandelate (norepinephrine/epinephrine), 5-HIAA (serotonin)

Sample Type:

First morning urine — single collection.