GenomicInsight® — Comprehensive Genomic Health Profile (DSL)

Description

GenomicInsight® — Comprehensive Genomic Health Profile

GenomicInsight® analyses clinically relevant genetic variants (SNPs) across key health pathways, translating your DNA into actionable lifestyle, nutritional, and therapeutic guidance. Unlike direct-to-consumer genetic tests, GenomicInsight® focuses on the variants that matter most clinically — those affecting methylation, detoxification, nutrient metabolism, cardiovascular risk, and hormonal health.

Genetic Pathways Analysed:

• Methylation & One-Carbon Metabolism: MTHFR (C677T, A1298C), MTR, MTRR, MTHFD1, BHMT, CBS — impacts folate metabolism, homocysteine, SAM/SAH ratio, and epigenetic regulation
• Detoxification (Phase I & II): CYP1A1, CYP1B1, CYP2C9, CYP2C19, CYP2D6, CYP3A4/5, GSTP1, GSTM1, GSTT1, NAT1/2, COMT, SOD2 — determines detox capacity and medication metabolism
• Neurotransmitter Metabolism: COMT (Val158Met), MAO-A, BDNF (Val66Met), SLC6A4 (serotonin transporter), DRD2/DRD4 — impacts mood, cognition, and stress response
• Cardiovascular Risk: APOE (ε2/ε3/ε4 — Alzheimer’s and lipid risk), MTHFR, ACE (I/D), PAI-1, eNOS, FV Leiden, Prothrombin G20210A
• Nutrient Metabolism: VDR (vitamin D receptor), FUT2 (B12 absorption), BCMO1 (beta-carotene → Vitamin A), FADS1/2 (omega-3 conversion), HFE (iron/haemochromatosis)
• Hormonal Health: CYP19A1 (aromatase — estrogen production), ESR1 (estrogen receptor), SHBG, AR (androgen receptor)
• Inflammation: TNF-α, IL-6, IL-1β, CRP polymorphisms — genetic inflammatory tendency

Sample Type:

Buccal swab (cheek swab) — simple at-home collection.