Cyrex Total Serum IgG / IgA / IgM

Description

Cyrex Total Serum IgG / IgA / IgM

This foundational immunoglobulin panel quantifies total circulating levels of the three main immunoglobulin classes in serum. It provides essential context for interpreting all other Cyrex antigen-specific antibody tests, and identifies immune deficiency, immune dysregulation, or hypergammaglobulinaemia that may affect results or indicate systemic immune dysfunction.

Immunoglobulins Measured:

• Total IgG: The dominant, long-term immune memory antibody — low levels indicate primary or secondary immune deficiency; elevated levels suggest chronic antigen stimulation or autoimmunity
• Total IgA: Mucosal and systemic immune defence — selective IgA deficiency is the most common primary immunodeficiency and causes falsely low results on IgA-based food reactivity tests
• Total IgM: Primary immune response antibody — elevated in early/acute infections; low in certain immunodeficiency syndromes

Clinical Applications:

• Baseline immune status before ordering Cyrex antigen panels
• Ruling out IgA deficiency before IgA-based reactivity tests (Arrays 3X, 4, 10)
• Immune deficiency screening
• Monitoring immunomodulatory treatments

Sample Type:

Blood serum — single blood draw.

Ref: HSE1572