Description
DUTCH Cycle Mapping + Plus™ (Female Only) — FINAL
Description
The DUTCH Cycle Mapping + Plus™ is the most comprehensive hormone test for cycling women, combining full-cycle hormone tracking, hormone metabolism analysis, adrenal function, and the Cortisol Awakening Response (CAR).
This advanced test provides a complete view of how hormones fluctuate throughout the menstrual cycle, how they are metabolized, and how the body responds to stress — helping uncover root causes of complex hormonal symptoms.
What This Test Measures
Cycle Mapping (Full Menstrual Cycle)
- Estrogen (E1, E2) patterns across the cycle
- Progesterone metabolites (α & β-pregnanediol)
- Ovulatory and luteal phase hormone trends
Hormone Metabolism
- Estrogen pathways (2-OH, 4-OH, 16-OH)
- Methylation markers
- Androgens (testosterone, DHEA, DHT)
Adrenal Function
- Diurnal cortisol rhythm
- Cortisol metabolites (total production)
- DHEA-S
Cortisol Awakening Response (CAR)
- Cortisol levels at waking, +30 min, +60 min
Organic Acid Markers (OATs)
- Oxidative stress (8-OHdG)
- Melatonin (6-OHMS)
- Vitamin B12 (methylmalonate)
- Vitamin B6 markers (xanthurenate, kynurenate)
- Neurotransmitters (dopamine, norepinephrine)
This test evaluates 35+ hormones, metabolites, and functional biomarkers in a single panel.
What You Learn
- Complete hormonal rhythm across the menstrual cycle
- Whether ovulation and progesterone production are optimal
- Estrogen metabolism and detoxification pathways
- Impact of stress on hormone balance
- Adrenal function and cortisol patterns
- Morning stress response and resilience (CAR)
- Nutritional, oxidative stress, and neurotransmitter status
Graph-based reports provide a visual representation of hormone fluctuations across the cycle, offering insights beyond single-day testing.
Who Should Consider This Test
- PCOS or irregular menstrual cycles
- Fertility concerns or hormone optimization
- Monthly migraines or PMS/PMDD
- Chronic fatigue, burnout, or stress-related issues
- Complex or long-standing hormonal imbalances
Sample Collection
- Daily first-morning urine samples across the cycle
- 4 additional urine samples on final day
- 5–6 saliva samples for CAR measurement
Why Choose DUTCH Over Other Tests?
Blood Testing
- Single-point measurement
Saliva Testing
- Limited metabolic insight
DUTCH Testing
- Measures hormones, metabolism, cycle patterns, and stress response together
Provides a complete and clinically actionable view of hormonal health
- Cycle Mapping + Plus™ → Most Comprehensive
- Cycle Mapping + Adrenals → Hormones + Stress Analysis
- Cycle Mapping + Sex Hormones → Focused Hormone Mapping





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