Description
DUTCH Adrenal — Cortisol & Adrenal Function Panel
The DUTCH Adrenal panel provides a comprehensive assessment of adrenal hormone production, cortisol metabolism, and DHEA levels using dried urine — offering far more detail than standard saliva or blood cortisol tests.
Key Biomarkers Measured:
- Free cortisol: Four timed measurements (morning, midday, evening, night) to plot the diurnal cortisol curve
- Free cortisone: The inactive cortisol metabolite, reflecting tissue-level cortisol activity
- Cortisol metabolites: THF, 5α-THF, THE — total cortisol production
- DHEA-S: Adrenal androgen and anti-aging hormone
- DHEA metabolites: Androsterone, Etiocholanolone
- Melatonin (6-OHMS): Sleep hormone, overnight marker
Who Should Order This Test:
- Fatigue, low energy, or poor stress tolerance
- Suspected adrenal insufficiency or HPA axis dysregulation
- Sleep disturbances
- Burnout or chronic stress
- Mood swings, anxiety, or depression
Sample Type:
Dried urine — 4 timed collections over one day.





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